3-phenyl-3-(p-tolyl)acrylaldehyde

Base Information

• Chemical Name: 3-phenyl-3-(p-tolyl)acrylaldehyde
• CAS No.: 3320-35-2
• Molecular Formula: C₁₆H₁₄O
• Molecular Weight: 222.287
• Mol file: 3320-35-2.mol

Synonyms:3-phenyl-3-(p-tolyl)acrylaldehyde

Chemical Property of 3-phenyl-3-(p-tolyl)acrylaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-phenyl-3-(p-tolyl)acrylaldehyde

There total 20 articles about 3-phenyl-3-(p-tolyl)acrylaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C18H18S2 → 3-phenyl-3-(p-tolyl)acrylaldehyde (3320-35-2)

Guidance literature:

With mercury dichloride; mercury(II) oxide; In water; acetonitrile; at 60 ℃; for 2h; diastereoselective reaction;

DOI:10.1002/ejoc.201600193

Reference yield: 86.0%

1-(4-methylphenyl)-1-phenyl-2-propyn-1-ol (88445-16-3,88445-17-4,13632-63-8) → 3-phenyl-3-(p-tolyl)acrylaldehyde (3320-35-2)

Guidance literature:

With [IrCp*(NCMe)₂(PPh₂Me)][hexafluorophosphate]₂; In dichloromethane-d2; at 20 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejic.201402882

Reference yield: 80.0%

(E)-3-phenyl-3-(p-tolyl)prop-2-en-1-ol → (E)-β-4-methylcinnamic aldehyde (3320-35-2)

Guidance literature:

With manganese(IV) oxide; In chloroform; at 20 ℃; for 72h; Inert atmosphere;

DOI:10.1016/j.tet.2011.10.051

upstream raw materials:

4-Methylbenzophenone

triethylamine

1-(4-methylphenyl)-1-phenyl-2-propyn-1-ol

2-(1,3-dithiolan-2-yl)-1-phenylethan-1-one

Downstream raw materials:

3-phenyl-3-(4-methylphenyl)propanal