Technology Process of 6-(4-fluorophenyl)pyrido[2′,1′:2,3]imidazo[4,5-c]quinoline
There total 10 articles about 6-(4-fluorophenyl)pyrido[2′,1′:2,3]imidazo[4,5-c]quinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,3,5-trichloro-2,4,6-triazine; tetrabutylammomium bromide;
In
water;
at 90 ℃;
for 1.75h;
DOI:10.1039/c4ra03415e
- Guidance literature:
-
With
iodine;
In
dimethyl sulfoxide;
at 95 ℃;
for 8h;
under 760.051 Torr;
Inert atmosphere;
Green chemistry;
DOI:10.1080/00397911.2021.2019278
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydrogencarbonate / N,N-dimethyl-formamide / 6 h / Heating
2: acetic acid; iron / 0.67 h / 90 °C
3: 1,3,5-trichloro-2,4,6-triazine; tetrabutylammomium bromide / water / 1.75 h / 90 °C
With
1,3,5-trichloro-2,4,6-triazine; tetrabutylammomium bromide; iron; sodium hydrogencarbonate; acetic acid;
In
water; N,N-dimethyl-formamide;
1: |Pictet-Spengler Synthesis / 3: |Pictet-Spengler Synthesis;
DOI:10.1039/c4ra03415e
