4-iodotetrahydro-2H-pyran

Base Information

Chemical Name:4-iodotetrahydro-2H-pyran
CAS No.:25637-18-7
Molecular Formula:C5H9IO
Molecular Weight:212.03
Hs Code.:29329990
European Community (EC) Number:639-329-5
DSSTox Substance ID:DTXSID20383726
Nikkaji Number:J1.004.436G
Wikidata:Q72484658
Mol file:25637-18-7.mol

Synonyms:4-iodotetrahydro-2H-pyran;25637-18-7;4-iodooxane;4-iodo-tetrahydropyran;4-IODOTETRAHYDROPYRAN;4-iodo-tetrahydro-2H-pyran;2H-PYRAN, TETRAHYDRO-4-IODO-;MFCD06797467;4-Iodo-tetrahydro-pyran;TETRAHYDRO-4-IODO-2H-PYRAN;4-Iodooxacyclohexane;4-Iodopentahydropyran;SCHEMBL172959;DTXSID20383726;JTRNQTFTRDPITG-UHFFFAOYSA-N;BCP11458;BBL101477;STL555273;AKOS005259354;4-Iodotetrahydro-2H-pyran, AldrichCPR;CS-W004278;GS-3890;PB13042;SY004489;AM20090312;FT-0648508;EN300-104914;A817935;W-206966

Suppliers and Price of 4-iodotetrahydro-2H-pyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Iodotetrahydro-2H-pyran
250mg
$ 372.00

TRC
4-Iodotetrahydro-2H-pyran
50mg
$ 60.00

SynQuest Laboratories
4-Iodotetrahydro-2H-pyran 97.0%
5 g
$ 165.00

SynQuest Laboratories
4-Iodotetrahydro-2H-pyran 97.0%
1 g
$ 55.00

Matrix Scientific
4-Iodo-tetrahydro-2H-pyran >95%
25g
$ 698.00

Matrix Scientific
4-Iodo-tetrahydro-2H-pyran >95%
5g
$ 235.00

JR MediChem
4-iodooxane 98%
100g
$ 518.00

JR MediChem
4-iodooxane 98%
500g
$ 1698.00

JR MediChem
4-iodooxane 98%
250g
$ 918.00

JR MediChem
4-iodooxane 98%
1kg
$ 2480.00

Total 78 raw suppliers

Chemical Property of 4-iodotetrahydro-2H-pyran

Chemical Property:

Vapor Pressure:0.313mmHg at 25°C
Refractive Index:1.546
Boiling Point:208.154 °C at 760 mmHg
Flash Point:79.689 °C
PSA：9.23000
Density:1.777 g/cm³
LogP:1.60040
Storage Temp.:2-8°C(protect from light)
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:211.96981
Heavy Atom Count:7
Complexity:50

Purity/Quality:

98%, ^*data from raw suppliers

4-Iodotetrahydro-2H-pyran ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCC1I

Technology Process of 4-iodotetrahydro-2H-pyran

There total 3 articles about 4-iodotetrahydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 2081-44-9
Tetrahydro-pyran-4-ol

: 25637-18-7
4-iodotetrahydropyran

Guidance literature:: With 1H-imidazole; iodine; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 16h; Cooling with ice; Inert atmosphere;
DOI:10.1021/jacs.7b04312

Reference yield:

: 97986-34-0
toluene-4-sulfonic acid tetrahydropyran-4-yl ester

: 25637-18-7
4-iodotetrahydropyran

Guidance literature:: With acetone; sodium iodide;
DOI:10.1039/jr9520000910

Reference yield:

: 108-97-4
4-pyrone

: 25637-18-7
4-iodotetrahydropyran

Guidance literature:: Multi-step reaction with 3 steps

1: Raney nickel / Hydrogenation

2: pyridine

3: acetone; sodium iodide

With pyridine; nickel; acetone; sodium iodide;
DOI:10.1039/jr9520000910