(5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride

Base Information

Chemical Name:(5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride
CAS No.:1187890-02-3
Molecular Formula:C₁₂H₁₂F₄N₂O*ClH
Molecular Weight:312.695
Hs Code.:

Synonyms:(5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride

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Technology Process of (5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride

There total 1 articles about (5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 932720-83-7
4-(5-fluoro-2-trifluoromethyl-benzoyl)-piperazine-1-carboxylic acid tert-butyl ester

: 1187890-02-3
(5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 0 ℃; for 0.25h;

Reference yield: 38.0%

: 108398-68-1
N-biphenyl-4-yl-malonamic acid

: 1187890-02-3
(5-fluoro-2-trifluoromethyl-phenyl)-piperazin-1-yl methanone hydrochloride

: 1187889-52-6
N-biphenyl-4-yl-3-[4-(5-fluoro-2-trifluoromethyl-benzoyl)-piperazin-1-yl]-3-oxo-propionamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 10 - 20 ℃;