(2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Base Information

Chemical Name:(2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol
CAS No.:1185750-55-3
Molecular Formula:C₄₉H₆₆O₆Si
Molecular Weight:779.145
Hs Code.:

(2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Synonyms:(2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Suppliers and Price of (2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

There total 10 articles about (2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 1185750-28-0
(2S,3R,4S,5E,7E)-1-(benzyloxy)-8-((2R,4R,5S,6S)-6-((S)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-2,4,6-trimethylocta-5,7-dien-3-ol

: 1185750-55-3
(2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2009.04.073

Reference yield:

: 1158955-70-4
(2R,3S,4S)-5-(tert-butyldiphenylsilyloxy)-3-hydroxy-N-methoxy-N,2,4-trimethylpentanamide

: 1185750-55-3
(2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Guidance literature:: Multi-step reaction with 6 steps

1.1: tetrahydrofuran / 4 h / -30 - 0 °C / Inert atmosphere

2.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

3.1: pyridinium p-toluenesulfonate / dichloromethane / Inert atmosphere; Reflux

4.1: triisopropoxytitanium(IV) chloride; cyclopentylmagnesium chloride / diethyl ether; hexane; toluene / 2 h / -78 - -30 °C / Inert atmosphere

4.2: 2 h / -30 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

6.1: diisobutylaluminium hydride / toluene / -78 - 20 °C / Inert atmosphere

With triisopropoxytitanium(IV) chloride; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; cyclopentylmagnesium chloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; toluene;
DOI:10.1016/j.tet.2009.04.073

Reference yield:

: 1185750-54-2
(2R,4R,5S,6S)-4-((1E,3E,5S,6R,7S)-8-(benzyloxy)-6-triethylsilyloxy-3,5,7-trimethylocta-1,3-dienyl)-2-(4-methoxyphenyl)-6-((S)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)-5-methyl-1,3-dioxane

: 1185750-55-3
(2S,3R,4S,5E,7E,9R,10S,11S,12S)-1-(benzyloxy)-13-(tert-butyldiphenylsilyloxy)-11-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltrideca-5,7-diene-3,9-diol

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

2: diisobutylaluminium hydride / toluene / -78 - 20 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; diisobutylaluminium hydride; In tetrahydrofuran; toluene;
DOI:10.1016/j.tet.2009.04.073