1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene

Base Information

• Chemical Name: 1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene
• CAS No.: 1332707-98-8
• Molecular Formula: C₂₈H₂₄F₂O₃
• Molecular Weight: 446.494
• Mol file: 1332707-98-8.mol

Synonyms:1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene

Chemical Property of 1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene

There total 2 articles about 1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(4-fluorophenyl)-(4-methoxyphenyl)-methanol (1426-55-7) → 1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene (1332707-98-8)

Guidance literature:

With sodium hydrogensulfite; at 150 ℃; for 1h; Neat (no solvent);

DOI:10.1002/cjoc.201190220

Reference yield:

4-fluoro-4'-methoxybenzophenone (345-89-1) → 1-((4-fluorophenyl)((4-fluorophenyl)(4-methoxyphenyl)methoxy)methyl)-4-methoxybenzene (1332707-98-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol

2: sodium hydrogensulfite / 1 h / 150 °C / Neat (no solvent)

With sodium tetrahydroborate; sodium hydrogensulfite; In methanol;

DOI:10.1002/cjoc.201190220

upstream raw materials:

4-fluoro-4'-methoxybenzophenone

(4-fluorophenyl)-(4-methoxyphenyl)-methanol