5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide

Base Information

Chemical Name:5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide
CAS No.:1198621-11-2
Molecular Formula:C₂₄H₂₃FN₂O₄
Molecular Weight:422.456
Hs Code.:

Synonyms:5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide

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Chemical Property of 5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide

Chemical Property:

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Technology Process of 5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide

There total 3 articles about 5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1198621-10-1
5-(benzyloxy)-N-(4-fluorobenzyl)-6-(hydroxymethyl)-4-(methoxymethyl)-N-methylnicotinamide

: 1198621-11-2
5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 20 ℃;

Reference yield:

: 1198621-09-8
3-(benzyloxy)-5-((4-fluorobenzyl)(methyl)carbamoyl)-4-(methoxymethyl)-2-methylpyridine 1-oxide

: 1198621-11-2
5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic anhydride / dichloromethane / 20 °C

2: manganese(IV) oxide / dichloromethane / 20 °C

With manganese(IV) oxide; trifluoroacetic anhydride; In dichloromethane;

Reference yield:

: 1198621-08-7
5-(benzyloxy)-N-(4-fluorobenzyl)-4-(methoxymethyl)-N,6-dimethylnicotinamide

: 1198621-11-2
5-(benzyloxy)-N-(4-fluorobenzyl)-6-formyl-4-(methoxymethyl)-N-methylnicotinamide

Guidance literature:: Multi-step reaction with 3 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 20 °C

2: trifluoroacetic anhydride / dichloromethane / 20 °C

3: manganese(IV) oxide / dichloromethane / 20 °C

With manganese(IV) oxide; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride; In dichloromethane;