N-(3-fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

Base Information

Chemical Name:N-(3-fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
CAS No.:627518-40-5
Molecular Formula:C₁₈H₁₆FN₃O₂
Molecular Weight:325.342
Hs Code.:
DSSTox Substance ID:DTXSID70430890
Nikkaji Number:J3.090.605E
Wikidata:Q27088285
Pharos Ligand ID:Y3GHGCL8KUDK
ChEMBL ID:CHEMBL120077
Mol file:627518-40-5.mol

Synonyms:(6,7-dimethoxy-2,4-dihydroindeno(1,2-c)pyrazol-3-yl)(3-fluorophenyl)amine;J101 compound;JNJ 10198409;JNJ-10198409;JNJ10198409;RWJ-540973

Suppliers and Price of N-(3-fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Tocris
JNJ10198409 ≥98%(HPLC)
50
$ 945.00

Tocris
JNJ10198409 ≥98%(HPLC)
10
$ 225.00

Sigma-Aldrich
JNJ-10198409 ≥98% (HPLC), solid
1mg
$ 201.00

Sigma-Aldrich
PDGFR Tyrosine Kinase Inhibitor IV
1mg
$ 185.00

Sigma-Aldrich
JNJ-10198409 ≥98% (HPLC), solid
5mg
$ 741.00

Crysdot
N-(3-Fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine 97%
1g
$ 1260.00

ChemScene
JNJ-10198409 >99.0%
1mg
$ 100.00

Chemenu
N-(3-Fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine 95+%
10mg
$ 4500.00

Cayman Chemical
JNJ-10198409 ≥98%
10mg
$ 183.00

Cayman Chemical
JNJ-10198409 ≥98%
5mg
$ 103.00

Total 12 raw suppliers

Chemical Property of N-(3-fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

Chemical Property:

Melting Point:171-173.5 °C
Boiling Point:528.8±50.0 °C(Predicted)
PKA:14.01±0.20(Predicted)
PSA：62.40000
Density:1.366±0.06 g/cm3(Predicted)
LogP:3.30270
Storage Temp.:−20°C
Solubility.:DMSO: >10mg/mL
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:325.12265492
Heavy Atom Count:24
Complexity:441

Purity/Quality:

>98% ^*data from raw suppliers

JNJ10198409 ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C2C(=C1)CC3=C2NN=C3NC4=CC(=CC=C4)F)OC

Technology Process of N-(3-fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

There total 1 articles about N-(3-fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 2107-69-9
5,6-dimethoxy-1-indanone

: 404-72-8
3-fluorophenyl isothiocyanate

: 627518-40-5
PDGF Receptor Tyrosine Kinase Inhibitor IV

Guidance literature:: 5,6-dimethoxy-1-indanone; 3-fluorophenyl isothiocyanate; With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 12h;

With acetic acid; hydrazine; In tetrahydrofuran; for 24h; Heating;
DOI:10.1021/jm050680m