N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

Base Information

Chemical Name:N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine
CAS No.:1146974-74-4
Molecular Formula:C₁₉H₂₇NO
Molecular Weight:285.429
Hs Code.:

Synonyms:N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

Suppliers and Price of N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

There total 6 articles about N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1146974-73-3
(1R,5R)-6-benzyl-7-isopropylbicyclo[3.3.1]non-6-en-3-one oxime

: 1146974-74-4
N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

Guidance literature:: With ethanol; sodium cyanoborohydride; trifluoroacetic acid; at 0 ℃; for 3h; Inert atmosphere;
DOI:10.1021/ol900441f

Reference yield:

: 1146974-50-6
(1R,2S,5S)-2-benzylbicyclo[3.3.1]nonane-3,7-dione

: 1146974-74-4
N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

Guidance literature:: Multi-step reaction with 5 steps

1: cerium(III) chloride / hexane; tetrahydrofuran / -78 - 0 °C / Inert atmosphere

2: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

3: silica gel / hexane / 10 h / Reflux; Inert atmosphere

4: pyridine; hydroxylamine hydrochloride / 3 h / 20 °C / Inert atmosphere

5: trifluoroacetic acid; sodium cyanoborohydride / ethanol / 3 h / 0 °C / Inert atmosphere

With pyridine; cerium(III) chloride; hydroxylamine hydrochloride; silica gel; sodium cyanoborohydride; triethylamine; trifluoroacetic acid; In tetrahydrofuran; ethanol; hexane; dichloromethane;
DOI:10.1021/ja509766f

Reference yield:

: 1146974-68-6
(1S,3S,4S,5R,7R)-4-benzyl-3-isopropyl-2-oxa-1-adamantanol

: 1146974-74-4
N-((1R,3S,5R)-6-benzyl-7-i-propylbicyclo[3.3.1]non-6-en-3-yl)hydroxylamine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

2: silica gel / hexane / 10 h / Reflux; Inert atmosphere

3: pyridine; hydroxylamine hydrochloride / 3 h / 20 °C / Inert atmosphere

4: trifluoroacetic acid; sodium cyanoborohydride / ethanol / 3 h / 0 °C / Inert atmosphere

With pyridine; hydroxylamine hydrochloride; silica gel; sodium cyanoborohydride; triethylamine; trifluoroacetic acid; In ethanol; hexane; dichloromethane;
DOI:10.1021/ja509766f