2-(Trimethylsilyl)ethanesulfonyl chloride

Base Information

• Chemical Name: 2-(Trimethylsilyl)ethanesulfonyl chloride
• CAS No.: 106018-85-3
• Molecular Formula: C5H13ClO2SSi
• Molecular Weight: 200.762
• Hs Code.: 2931900090
• European Community (EC) Number: 628-168-6
• DSSTox Substance ID: DTXSID20431554
• Nikkaji Number: J1.512.977H
• Wikidata: Q72514442
• Mol file: 106018-85-3.mol

Synonyms:2-(Trimethylsilyl)ethanesulfonyl chloride;106018-85-3;2-trimethylsilylethanesulfonyl Chloride;2-(trimethylsilyl)ethane-1-sulfonyl chloride;Ethanesulfonyl chloride, 2-(trimethylsilyl)-;2-(TRIMETHYLSILYL)ETHANESULFONYL CHLORI;2-Trimethylsilanyl-ethanesulfonyl Chloride;SCHEMBL1115359;DTXSID20431554;BLPMCIWDCRGIJV-UHFFFAOYSA-N;BBL103567;MFCD09265153;STL557377;2-(trimethylsilyl)ethylsulfonylchloride;AKOS006336239;2-trimethylsilanylethanesulfonyl chloride;s11291;beta-trimethylsilylethanesulfonyl chloride;AS-54524;FT-0720569;2-(TRIMETHYLSILYL)ETHANESULFONYLCHLORIDE;EN300-262942;2-(TRIMETHYLSILYL)ETHANESULFONYL CHLORI&;J-001521

Chemical Property of 2-(Trimethylsilyl)ethanesulfonyl chloride

Chemical Property:

• Refractive Index: n20/D 1.4444
• Boiling Point: 209.429 °C at 760 mmHg
• Flash Point: 80.46 °C
• PSA: 42.52000
• Density: 1.12 g/cm³
• LogP: 2.97400
• Storage Temp.: 2-8°C
• Solubility.: Sol most common organic solvents.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 200.0094051
• Heavy Atom Count: 10
• Complexity: 187

Purity/Quality:

97% ^*data from raw suppliers

2-(Trimethylsilyl)ethanesulfonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): FXi
• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)CCS(=O)(=O)Cl
• Physical properties: bp 60 °C/0.1 mmHg; yellow oil.
• Uses: β-Trimethylsilylethanesulfonyl Chloride is used in the protection of primary and secondary amines as their sulfonamides, which are cleaved by fluoride ion. It participates in the reations of Protection of Amines, SESCl in Synthesis, N-Alkylation, Deprotection Conditions, Formation of 2-Trimethylsilylethanesulfonylimines, the (N-SES-Imino) Phenyliodinane or SESN=IPh Reagent, SES-N3, etc. 2-(Trimethylsilyl)ethanesulfonyl Chloride can be prepared to used to treat cancer and other diseases.