H-89 DIHYDROCHLORIDE HYDRATE

Base Information

• Chemical Name: H-89 DIHYDROCHLORIDE HYDRATE
• CAS No.: 130964-39-5
• Molecular Formula: C₂₀H₂₀BrN₃O₂S*2ClH
• Molecular Weight: 519.29
• Hs Code.: 2935909099
• Mol file: 130964-39-5.mol

Synonyms:5-Isoquinolinesulfonamide,N-[2-[[3-(4-bromophenyl)-2-propenyl]amino]ethyl]-, dihydrochloride (9CI); H 89dihydrochloride

Chemical Property of H-89 DIHYDROCHLORIDE HYDRATE

Chemical Property:

• Melting Point: 195-200℃
• PSA: 88.70000
• LogP: 6.98090
• Storage Temp.: 2-8°C
• Solubility.: H2O: ≥10mg/mL

Purity/Quality:

98%Min ^*data from raw suppliers

N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolineSulfonamideDihydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: H-89 dihydrochloride hydrate has been used in the inhibition of protein kinase A in Leydig cells, primary calvarial osteoblasts (pOBs), rat granulosa cell line (LH-15 cells) and human umbilical vein endothelial cells (HUVECs). Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase) with an inhibitory constant of 0.0048 uM.

Technology Process of H-89 DIHYDROCHLORIDE HYDRATE

There total 1 articles about H-89 DIHYDROCHLORIDE HYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-[2-[[3-(4-bromophenyl)-2-propenyl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride (130964-39-5)

Guidance literature:

Refernces