5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Base Information

Chemical Name:5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine
CAS No.:1101864-07-6
Molecular Formula:C₃₆H₃₈N₆O₆
Molecular Weight:650.734
Hs Code.:

5'-O-dimethoxytrityl-N<sub>2</sub>-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Synonyms:5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Suppliers and Price of 5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Chemical Property:

Purity/Quality:: ≥ 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

There total 3 articles about 5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1140234-13-4
N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 1101864-07-6
5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Guidance literature:: With pyridine; dmap; triethylamine; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1002/anie.201100078

Reference yield:

: 1273552-46-7
8-brom-N₂-[(dimethylamino)methylene]-3',5'-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine

: 1101864-07-6
5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 12 h / 95 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

3: pyridine; dmap; triethylamine / 16 h / 20 °C / Inert atmosphere

With pyridine; dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; toluene;
DOI:10.1002/anie.201100078

Reference yield:

: 1273552-45-6
N₂-[(dimethylamino)methylene]-3',5'-O-(tert-butyldimethylsilyl)-8-vinyl-2'-deoxyguanosine

: 1101864-07-6
5'-O-dimethoxytrityl-N₂-[(dimethylamino)methylene]-8-vinyl-2'-deoxyguanosine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2: pyridine; dmap; triethylamine / 16 h / 20 °C / Inert atmosphere

With pyridine; dmap; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran;
DOI:10.1002/anie.201100078