(3S)-1-Iodo-3-(tert-butyldimethylsilyloxy)-1-octene

Base Information

Chemical Name:(3S)-1-Iodo-3-(tert-butyldimethylsilyloxy)-1-octene
CAS No.:63358-20-3
Molecular Formula:C14H29 I O Si
Molecular Weight:368.36900
Hs Code.:2931900090

Synonyms:Silane,(1,1-dimethylethyl)[[1-(2-iodoethenyl)hexyl]oxy]dimethyl-, (S)-; (3S)-1-Iodo-3-(tert-butyldimethylsilyloxy)-1-octene

Suppliers and Price of (3S)-1-Iodo-3-(tert-butyldimethylsilyloxy)-1-octene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (3S)-1-Iodo-3-(tert-butyldimethylsilyloxy)-1-octene

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:324.109oC at 760 mmHg
Flash Point:149.816oC
PSA：9.23000
Density:1.170
LogP:5.90580

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3S)-1-Iodo-3-(tert-butyldimethylsilyloxy)-1-octene

There total 6 articles about (3S)-1-Iodo-3-(tert-butyldimethylsilyloxy)-1-octene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50999-83-2
(S)-tert-butyl-(1-ethynylhexyloxy)dimethylsilane

: 63358-20-3
C₁₄H₂₉IOSi

Guidance literature:: (S)-tert-butyl-(1-ethynylhexyloxy)dimethylsilane; With zirconocene dichloride; lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; at 20 ℃; for 0.666667h;

With iodine; In tetrahydrofuran; for 0.5h; Darkness;
DOI:10.1016/j.tetlet.2019.151331

Reference yield:

: 121563-58-4
(S)-2-((tert-butyldimethylsilyl)oxy)heptan-1-ol

: 63358-20-3
C₁₄H₂₉IOSi

Guidance literature:: Multi-step reaction with 4 steps

1.1: Dess-Martin periodane; sodium hydrogencarbonate / dichloromethane / 1.5 h / 20 °C

2.1: triphenylphosphine; zinc / dichloromethane / 24 h

2.2: 2.5 h

3.1: methyllithium / diethyl ether / 1 h / -78 °C / Inert atmosphere

4.1: zirconocene dichloride; lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 0.67 h / 20 °C

4.2: 0.5 h / Darkness

With zirconocene dichloride; methyllithium; sodium hydrogencarbonate; Dess-Martin periodane; lithium tri-t-butoxyaluminum hydride; triphenylphosphine; zinc; In tetrahydrofuran; diethyl ether; dichloromethane; 3.1: |Corey-Fuchs Alkyne Synthesis;
DOI:10.1016/j.tetlet.2019.151331

Reference yield:

: 97211-25-1
2-<(tert-butyldimethylsilyl)oxy>heptan-1-al

: 63358-20-3
C₁₄H₂₉IOSi

Guidance literature:: Multi-step reaction with 3 steps

1.1: triphenylphosphine; zinc / dichloromethane / 24 h

1.2: 2.5 h

2.1: methyllithium / diethyl ether / 1 h / -78 °C / Inert atmosphere

3.1: zirconocene dichloride; lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 0.67 h / 20 °C

3.2: 0.5 h / Darkness

With zirconocene dichloride; methyllithium; lithium tri-t-butoxyaluminum hydride; triphenylphosphine; zinc; In tetrahydrofuran; diethyl ether; dichloromethane; 2.1: |Corey-Fuchs Alkyne Synthesis;
DOI:10.1016/j.tetlet.2019.151331