1,2-O-Ditetradecyl-rac-glycerol

Base Information

• Chemical Name: 1,2-O-Ditetradecyl-rac-glycerol
• CAS No.: 36314-51-9
• Molecular Formula: C31H64 O3
• Molecular Weight: 484.847
• Hs Code.: 2909499000
• Mol file: 36314-51-9.mol

Synonyms:1-Propanol,2,3-bis(tetradecyloxy)-, (S)-; 1,2-Di-O-tetradecyl-sn-glycerol;1,2-Ditetradecyl-sn-glycerol

Chemical Property of 1,2-O-Ditetradecyl-rac-glycerol

Chemical Property:

• Melting Point: 44-45 °C
• Boiling Point: 567.5±30.0 °C(Predicted)
• PKA: 14.23±0.10(Predicted)
• PSA: 38.69000
• Density: 0.880±0.06 g/cm3(Predicted)
• LogP: 9.78270

Purity/Quality:

97% ^*data from raw suppliers

1,2-Ditetradecyl-sn-glycerol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,2-Ditetradecyl-sn-glycerol is used in the synthesis of cationic cardiolipin analogs.

Technology Process of 1,2-O-Ditetradecyl-rac-glycerol

There total 7 articles about 1,2-O-Ditetradecyl-rac-glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(R)-2,3-Bis-tetradecyloxy-propionaldehyde (128229-35-6) → (R)-1,2-bis-tetradecyloxy propane-3-ol (36314-51-9)

Guidance literature:

With methanol; sodium tetrahydroborate; at 25 ℃; for 6h;

DOI:10.1039/c39900000378

Reference yield: 92.0%

(R)-1,2-bis-tetradecyloxy-3-O-benzylpropane (36314-50-8) → (R)-1,2-bis-tetradecyloxy propane-3-ol (36314-51-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 12h; under 2585.81 Torr;

DOI:10.1016/j.tetlet.2004.02.044

Reference yield:

1-Bromotetradecane (112-71-0) → (R)-1,2-bis-tetradecyloxy propane-3-ol (36314-51-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / NaH / dimethylformamide / 16 h / 20 - 60 °C

2: 89 percent / hydrogen / Pd/C / ethyl acetate / 4 h / 2585.81 Torr

With hydrogen; sodium hydride; palladium on activated charcoal; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.bioorg.2005.06.001

upstream raw materials:

(R)-2,3-Bis-tetradecyloxy-propionaldehyde

(R)-1,2-bis-tetradecyloxy-3-O-benzylpropane

1-Bromotetradecane

(2R,3S,4S,5R)-1,2,5,6-Tetrakis-tetradecyloxy-hexane-3,4-diol

Downstream raw materials:

3-O-(3,6-Di-O-acetyl-2,4-di-O-benzyl-α-D-mannopyranosyl)-1,2-di-O-tetradecyl-sn-glycerol

(2R,3R,4S,5S,6R)-2-(2,3-Bis-tetradecyloxy-propoxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol

3-O-α-D-Mannopyranosyl-1,2-di-O-tetradecyl-sn-glycerol

3-O-α-D-Galactopyranosyl-1,2-di-O-tetradecyl-sn-glycerol