(2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

Base Information

Chemical Name:(2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine
CAS No.:1185355-81-0
Molecular Formula:C₃₁H₃₈N₂O₃
Molecular Weight:486.654
Hs Code.:

Synonyms:(2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

Suppliers and Price of (2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

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Technology Process of (2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

There total 1 articles about (2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1185355-78-5
(2R,4R)-4-azido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

: 108-24-7
acetic anhydride

: 1185355-81-0
(2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

Guidance literature:: With 5% Pd(II)/C(eggshell); hydrogen; triethylamine; In ethyl acetate; at 20 ℃; for 12h; under 760.051 Torr;
DOI:10.1039/b904948g

Reference yield: 83.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1185355-81-0
(2R,4R)-4-acetamido-2-[(S)-1,2-dibenzyloxyethyl]-1-[(S)-1-phenylethyl]piperidine

: 1185355-83-2
(2R,4R)-4-acetamido-1-tert-butoxycarbonyl-2-[(S)-1,2-dibenzyloxyethyl]piperidine

Guidance literature:: With 20 % Pd(OH)2/C; hydrogen; In ethanol; at 20 ℃; for 3h; under 760.051 Torr; chemoselective reaction;
DOI:10.1039/b904948g