MIRODENAFIL

Base Information

• Chemical Name: MIRODENAFIL
• CAS No.: 862189-95-5
• Molecular Formula: C26H37N5O5S
• Molecular Weight: 531.67
• Mol file: 862189-95-5.mol

Synonyms:1-Piperazineethanol,4-[[3-(5-ethyl-4,5-dihydro-4-oxo-7-propyl-1H-pyrrolo[3,2-d]pyrimidin-2-yl)-4-propoxyphenyl]sulfonyl]-(9CI);Mirodenafil;

Chemical Property of MIRODENAFIL

Chemical Property:

• Boiling Point: 730.447 °C at 760 mmHg
• PKA: 14.96±0.10(Predicted)
• Flash Point: 395.56 °C
• PSA: 129.14000
• Density: 1.339 g/cm³
• LogP: 3.40800

Purity/Quality:

99% ^*data from raw suppliers

Mirodenafil 98+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Mirodenafil (Mvix), a second-generation PDE5i, was launched in Korea in November 2007, and its orally dissolving film (Mvix S) was launched in December 2011. The product is available in tablet formulation or orally dissolving film of 50 and 100 mg. Mirodenafil has been approved only in Korea. Its pharmacokinetic profiles include a Tmax of 1.25 h, T1/2 of 2.5 h, and a IC50 for PDE5 of 0.34 nmol/L, which would confer a biochemical property of relatively high affinity (potency) for PDE5. While the pharmacokinetic profile is similar to that of sildenafil, mirodenafil appears to be 10 times more selective for PDE5 than sildenafil.