N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine

Base Information

Chemical Name:N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine
CAS No.:1145785-99-4
Molecular Formula:C₂₄H₂₄FN₅O
Molecular Weight:417.486
Hs Code.:

Synonyms:N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine

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Chemical Property of N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine

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Technology Process of N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine

There total 2 articles about N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1145786-45-3
[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]boronic acid

: 1145786-64-6
6-chloro-N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-3-pyridazinamine

: 1145786-44-2
4-methyl-1-[2-(methyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazole

: 1145785-99-4
N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine

Guidance literature:: With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,2-dimethoxyethane; water; at 80 ℃; for 24h;

Reference yield:

: C₁₆H₁₅ClN₄O

: 66399-30-2
(S)-1-(4-Fluoro-phenyl)-ethylamine

: 1145785-99-4
N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine

Guidance literature:: With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine; In toluene; Reflux;
DOI:10.1016/j.bmcl.2011.04.143