Technology Process of C24H34N6O6
There total 5 articles about C24H34N6O6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C20H26N2O6;
With
4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 0.0833333h;
Inert atmosphere;
2-(2-azidoethoxy)ethanamine hydrochloride;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol200861f
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0 °C / Inert atmosphere
1.2: pH 2 - 3 / Inert atmosphere
2.1: 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0 °C / Inert atmosphere
3.2: pH 2 - 3 / Inert atmosphere
4.1: 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere
4.2: 0 - 20 °C / Inert atmosphere
With
4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/ol200861f
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate; potassium iodide / acetone / 24 h / Inert atmosphere; Reflux
2.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0 °C / Inert atmosphere
2.2: pH 2 - 3 / Inert atmosphere
3.1: 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere
3.2: 0 - 20 °C / Inert atmosphere
4.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0 °C / Inert atmosphere
4.2: pH 2 - 3 / Inert atmosphere
5.1: 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere
5.2: 0 - 20 °C / Inert atmosphere
With
4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium iodide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ol200861f