(R)-2-Nonanamine

Base Information

• Chemical Name: (R)-2-Nonanamine
• CAS No.: 74069-74-2
• Molecular Formula: C9H21N
• Molecular Weight: 143.272
• Hs Code.: 2921199090
• Mol file: 74069-74-2.mol

Synonyms:2-Nonanamine,(R)-;(R)-2-Nonanamine;

Chemical Property of (R)-2-Nonanamine

Chemical Property:

• Vapor Pressure: 0.526mmHg at 25°C
• Melting Point: <-20 °C
• Refractive Index: 1.4271
• Boiling Point: 191 °C at 760 mmHg
• Flash Point: 69.8 °C
• PSA: 26.02000
• Density: 0.79 g/cm³
• LogP: 3.39440
• Sensitive.: Air Sensitive

Purity/Quality:

99% ^*data from raw suppliers

(R)-(-)-2-AMINONONANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C,N
• Hazard Codes: C,N
• Statements: 34-50/53-35-20/21/22
• Safety Statements: 26-36/37/39-45-61

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-2-Nonanamine

There total 2 articles about (R)-2-Nonanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Nonanone (821-55-6) → (R)-2-aminononane (74069-74-2)

Guidance literature:

With D-Glucose; D-Alanine; Neosartorya fischeri (R)-selective amine transaminase; pyridoxal 5'-phosphate; NADH; In water; at 30 ℃; pH=7.5; aq. sodium phosphate buffer; Enzymatic reaction;

DOI:10.1002/adsc.201100435

Reference yield:

(S)-(+)-2-aminononane (869278-88-6) + (R)‐2‐aminohexane (5329-79-3,68107-05-1,70095-40-8,70492-67-0) → (R)-2-aminononane (74069-74-2) + (S)-hexan-2-amine (70492-67-0)

Guidance literature:

With Chromobacterium violaceum ATA-114 1100708MW; ωTA ATA-117 102907WW; pyridoxal 5'-phosphate; at 30 ℃; for 24h; pH=7; aq. phosphate buffer;

DOI:10.1002/chem.201001602

Reference yield: 100.0%

(R)-2-aminononane (74069-74-2) + 1-chloro-2,4-dinitro-benzene (97-00-7) → (R)-2,4-dinitro-N-(nonan-2-yl)aniline

Guidance literature:

In ethanol; at 140 ℃; for 0.166667h; Microwave irradiation;

DOI:10.1016/j.tet.2021.131925

upstream raw materials:

(S)-(+)-2-aminononane

(R)‐2‐aminohexane

2-Nonanone

Downstream raw materials:

2-Nonanone

(S)-(+)-2-aminononane

(R)‐2‐aminohexane

Refernces

• 1、 Chen, Fei-Fei,Zheng, Gao-Wei,Liu, Lei,Li, Hao,Chen, Qi,Li, Fu-Long,Li, Chun-Xiu,Xu, Jian-He. "Reshaping the Active Pocket of Amine Dehydrogenases for Asymmetric Synthesis of Bulky Aliphatic Amines". . p. 2622 - 2628. Retrieved 2018/03/13.
• 2、 Schaetzle, Sebastian,Steffen-Munsberg, Fabian,Thontowi, Ahmad,Hoehne, Matthias,Robins, Karen,Bornscheuer, Uwe T.. "Enzymatic asymmetric synthesis of enantiomerically pure aliphatic, aromatic and arylaliphatic amines with (R)-selective amine transaminases". experimental part. p. 2439 - 2445. Retrieved 2011/11/06.