propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

Base Information

Chemical Name:propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate
CAS No.:1416320-49-4
Molecular Formula:C₂₆H₂₇Cl₃N₄O₃
Molecular Weight:549.884
Hs Code.:

Synonyms:propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

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Chemical Property of propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

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Technology Process of propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

There total 5 articles about propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 1416320-59-6
4-nitrophenyl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

: 67-63-0,8013-70-5
isopropyl alcohol

: 1416320-49-4
propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

Guidance literature:: 4-nitrophenyl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate; isopropyl alcohol; With sodium hydride; In tetrahydrofuran; Pionier 2076; for 16h;

With acetic acid; In tetrahydrofuran; Pionier 2076;

Reference yield:

: 87120-72-7
1-(tert-butoxycarbonyl)-4-aminopiperidine

: 1416320-49-4
propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine / tetrahydrofuran / 16 h

2: trifluoroacetic acid / dichloromethane / 16 h

3: triethylamine / tetrahydrofuran / 16 h

4: sodium hydride / tetrahydrofuran; Pionier 2076 / 16 h

With sodium hydride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; Pionier 2076;

Reference yield:

: 162758-35-2
rimonabant acid

: 1416320-49-4
propan-2-yl-4-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-amido]piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine / tetrahydrofuran / 16 h

2: trifluoroacetic acid / dichloromethane / 16 h

3: triethylamine / tetrahydrofuran / 16 h

4: sodium hydride / tetrahydrofuran; Pionier 2076 / 16 h

With sodium hydride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; Pionier 2076;