2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

Base Information

Chemical Name:2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide
CAS No.:1394036-61-3
Molecular Formula:C₂₁H₃₀F₃N₃O₄S
Molecular Weight:477.548
Hs Code.:

Synonyms:2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

Suppliers and Price of 2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

There total 3 articles about 2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.1%

: 1648-99-3
2,2,2-Trifluoroethanesulfonyl chloride

: trans-4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexylamine hydrochloride

: 1394036-61-3
2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

Reference yield:

: 215790-29-7
1,1-dimethylethyl[trans-4-(2-oxoethyl)cyclohexyl]carbamate

: 1394036-61-3
2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane; methanol / 2 h / 20 °C

1.2: 16 h / 20 °C

2.1: hydrogenchloride / dichloromethane; 1,4-dioxane / 2 h / 20 °C

3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

With hydrogenchloride; triethylamine; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; methanol; dichloromethane;

Reference yield:

: 1417564-98-7
trans-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperazin-1-yl)ethyl]cyclohexyl}carbamic acid tert-butyl ester

: 1394036-61-3
2,2,2-trifluoroethanesulfonic acid trans-N-{4-[2-(4-benzo[1,3]dioxol-4-ylpiperazin-1-yl)ethyl]cyclohexyl}amide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / dichloromethane; 1,4-dioxane / 2 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane;