4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride

Base Information

• Chemical Name: 4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride
• CAS No.: 58033-01-5
• Molecular Formula: C₃₃H₄₁NO₂*ClH
• Molecular Weight: 520.155

Synonyms:4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride

Chemical Property of 4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride

Chemical Property:

Purity/Quality:

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Technology Process of 4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride

There total 1 articles about 4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethereal HCl + C18H21NO (115-46-8) + 1-(4-(tert-butyl)phenyl)-5-chloropentan-1-one (58012-89-8) → 4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride (58033-01-5)

Guidance literature:

With potassium iodide; potassium hydrogencarbonate; In toluene;

Reference yield:

4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride (58033-01-5) → 4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone oxime hydrochloride

Guidance literature:

With hydrogenchloride; hydroxylamine hydrochloride; In pyridine; methanol;

Reference yield:

methanolic potassium hydroxide + 4'-tert-butyl-5-[4-(α-hydroxy-α-phenylbenzyl)piperidino]valerophenone hydrochloride (58033-01-5) → 5-(4'-(hydroxy(diphenyl)methyl)piperidin-1-yl)-1-(4-tert-butylphenyl)pentan-1-ol

Guidance literature:

In methanol; sodium borohydrid;

upstream raw materials:

C₁₈H₂₁NO

1-(4-(tert-butyl)phenyl)-5-chloropentan-1-one

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