3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine

Base Information

• Chemical Name: 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine
• CAS No.: 87401-16-9
• Molecular Formula: C₃₀H₂₈N₂O₂
• Molecular Weight: 448.565
• Mol file: 87401-16-9.mol

Synonyms:3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine

Chemical Property of 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine

There total 3 articles about 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

benzalacetophenone (94-41-7) + 1-(Phenylethylaminocarbonylmethyl)pyridinium chloride (87401-07-8) → 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine (87401-16-9)

Guidance literature:

With sodium hydroxide; In ethanol; at 60 ℃;

Reference yield:

1-(methoxycarbonylmethyl)pyridinium chloride (18667-21-5) → 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine (87401-16-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / ethanol / 3 h / 25 °C

2: 91 percent / NaOH / ethanol / 60 °C

With sodium hydroxide; In ethanol;

Reference yield:

phenethylamine (64-04-0) → 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine (87401-16-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / ethanol / 3 h / 25 °C

2: 91 percent / NaOH / ethanol / 60 °C

With sodium hydroxide; In ethanol;

upstream raw materials:

benzalacetophenone

1-(Phenylethylaminocarbonylmethyl)pyridinium chloride

1-(methoxycarbonylmethyl)pyridinium chloride

phenethylamine