5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one

Base Information

• Chemical Name: 5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one
• CAS No.: 717123-10-9
• Molecular Formula: C₁₃H₁₆O₅
• Molecular Weight: 252.267
• Mol file: 717123-10-9.mol

Synonyms:5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one

Chemical Property of 5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one

There total 1 articles about 5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5-[(4-methoxyphenoxy)methyl]-5-[(phenylmethoxy)methyl]-3,4,5-trihydrofuran-2-one (213828-30-9) → 5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one (717123-10-9)

Guidance literature:

With boron trichloride; In dichloromethane; at -78 ℃; for 2h;

DOI:10.1021/jm030610k

Reference yield:

(3,4-dihydro-2H-pyran-2-yl-methoxymethyl)polystyrene + 5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one (717123-10-9) → C20H27O7Pol

Guidance literature:

With pyridinium p-toluenesulfonate; In 1,2-dichloro-ethane; at -30 - 60 ℃; solid phase reaction;

DOI:10.1021/jm8001907

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) + 5-(hydroxymethyl)-5-[(4-methoxyphenoxy)methyl]-3,4,5-trihydrofuran-2-one (717123-10-9) → C29H34O5Si

Guidance literature:

With 1H-imidazole; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1021/jm8001907

upstream raw materials:

5-[(4-methoxyphenoxy)methyl]-5-[(phenylmethoxy)methyl]-3,4,5-trihydrofuran-2-one