N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide

Base Information

Chemical Name:N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide
CAS No.:1239890-85-7
Molecular Formula:C₂₉H₃₄N₂O₇
Molecular Weight:522.598
Hs Code.:

Synonyms:N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide

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Technology Process of N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide

There total 2 articles about N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.2%

: 66671-69-0
N,N'-bis(2-hydroxyethyl)-2,2'-oxidiacetamide

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 1239890-85-7
N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide

Guidance literature:: With pyridine; at 0 ℃; Inert atmosphere;
DOI:10.1021/bc100202y

Reference yield:

: 1239890-83-5
N,N'-bis[2-(tert-butyldimethylsilyloxy)ethyl]-2,2'-oxidiacetamide

: 1239890-85-7
N-[2-(4,4'-dimethoxytrityl)oxyethyl]-N'-(2-hydroxyethyl)-2,2'-oxidiacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / ethanol; water / 0.25 h / Inert atmosphere

2: pyridine / 0 °C / Inert atmosphere

With pyridine; hydrogenchloride; In ethanol; water;
DOI:10.1021/bc100202y