4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate

Base Information

Chemical Name:4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate
CAS No.:105786-95-6
Molecular Formula:C6H8 N2 O2
Molecular Weight:140.14
Hs Code.:2934999090
European Community (EC) Number:844-437-2
DSSTox Substance ID:DTXSID20474325
NSC Number:24711
Wikidata:Q72506829
Mol file:105786-95-6.mol

Synonyms:105786-95-6;4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate;Tetrahydropyrido[c]sydnone;4,5,6,7-tetrahydrooxadiazolo[3,4-a]pyridin-8-ium-3-olate;4,5,6,7-Tetrahydro-3-hydroxy-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium inner salt;MFCD13194917;NSC24711;OBCUGZUJWKHNHA-UHFFFAOYSA-N;SCHEMBL2525004;DTXSID20474325;4,5,6,7-tetrahydro[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate;NSC-24711;AKOS016003885;AM802879;AS-39678;SY205215;CS-0046948;FT-0706498;EN300-244260;4,5,6,7-tetrahydro[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium 3-olate;4H,5H,6H,7H-8lambda5-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ylium-3-olate

Suppliers and Price of 4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,5,6,7-Tetrahydro-3-hydroxy-[1,2,3]oxadiazolo[3,4-a]pyridin-8-iumInnerSalt
100mg
$ 185.00

SynQuest Laboratories
4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate
1 g
$ 832.00

Medical Isotopes, Inc.
4,5,6,7-Tetrahydro-3-hydroxy-[1,2,3]oxadiazolo[3,4-α]pyridin-8-iumInnerSalt
1 g
$ 2400.00

Medical Isotopes, Inc.
4,5,6,7-Tetrahydro-3-hydroxy-[1,2,3]oxadiazolo[3,4-α]pyridin-8-iumInnerSalt
100 mg
$ 675.00

Crysdot
4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate 95+%
5g
$ 823.00

Apolloscientific
4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate
1g
$ 702.00

American Custom Chemicals Corporation
4,5,6,7-TETRAHYDRO-[1,2,3]OXADIAZOLO[3,4-A]PYRIDIN-8-IUM-3-OLATE 95.00%
5MG
$ 496.24

Alichem
4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate
1g
$ 232.96

Alichem
4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate
5g
$ 677.25

Total 12 raw suppliers

Chemical Property of 4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate

Chemical Property:

PSA：52.97000
LogP:0.44220
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:140.058577502
Heavy Atom Count:10
Complexity:131

Purity/Quality:

97% ^*data from raw suppliers

4,5,6,7-Tetrahydro-3-hydroxy-[1,2,3]oxadiazolo[3,4-a]pyridin-8-iumInnerSalt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC[N+]2=NOC(=C2C1)[O-]
Uses 4,5,6,7-Tetrahydro-3-hydroxy-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium Inner Salt is a useful synthetic intermediate. It is used to prepare fused bicyclic heterocycles as potent and selective 5-HT2A receptor antagonists for the treatment of insomnia. It is also used to synthesize β-?Lactamase Inhibitors.

Technology Process of 4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate

There total 7 articles about 4,5,6,7-Tetrahydro-[1,2,3]oxadiazolo[3,4-a]pyridin-8-ium-3-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4515-18-8,30310-81-7
1-nitroso-piperidine-2-carboxylic acid

: 105786-95-6
4,5,6,7-tetrahydro<1.2.3>oxadiazolo<3,4-a>pyridin-3-one

Guidance literature:: With chloroformic acid ethyl ester; triethylamine; In acetone; at 0 ℃; for 0.5h;

Reference yield: 82.0%

: 4043-87-2,83680-83-5
pipecolic Acid

: 105786-95-6
4,5,6,7-tetrahydro<1.2.3>oxadiazolo<3,4-a>pyridin-3-one

Guidance literature:: pipecolic Acid; With hydrogenchloride; sodium nitrite; In water; at -10 - 20 ℃;

With trifluoroacetic anhydride; In diethyl ether; at -5 - 20 ℃;