C₉H₆ClN₃O

Base Information

• Chemical Name: C₉H₆ClN₃O
• CAS No.: 1282042-03-8
• Molecular Formula: C₉H₆ClN₃O
• Molecular Weight: 207.619
• Mol file: 1282042-03-8.mol

Synonyms:C₉H₆ClN₃O

Chemical Property of C₉H₆ClN₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₉H₆ClN₃O

There total 1 articles about C₉H₆ClN₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dichloropyridine-4-carboxylic acid (5398-44-7) → C9H6ClN3O (1282042-03-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: methanol / 48 h / 80 °C

2.1: tetrahydrofuran / 1 h / -45 - 0 °C

2.2: 0.5 h / -25 °C

3.1: 1 h / 130 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 100 °C

5.1: hydrogenchloride / 4 h / 80 °C

With hydrogenchloride; potassium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.01.017

Reference yield:

C9H6ClN3O (1282042-03-8) → C21H22N4O3 (1282042-18-5)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium tert-butoxide / acetone / 24 h / 80 °C

2: N-ethyl-N,N-diisopropylamine / 0 - 150 °C

With N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; In acetone;

DOI:10.1016/j.bmcl.2011.01.017

Reference yield:

C9H6ClN3O (1282042-03-8) → C21H22N4O3 (1282042-20-9)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium tert-butoxide / acetone / 24 h / 80 °C

2: N-ethyl-N,N-diisopropylamine / 0 - 150 °C

With N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; In acetone;

DOI:10.1016/j.bmcl.2011.01.017

upstream raw materials:

2,6-dichloropyridine-4-carboxylic acid

Downstream raw materials:

C₂₀H₂₂N₄O₂

C₂₀H₂₂N₄O₂

C₂₁H₂₂N₄O

C₂₂H₂₄N₄O₂