Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester

Base Information

• Chemical Name: Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester
• CAS No.: 75812-59-8
• Molecular Formula: C₂₅H₃₃O₃P
• Molecular Weight: 412.509
• Mol file: 75812-59-8.mol

Synonyms:Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester

Chemical Property of Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester

There total 2 articles about Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-hydroxyheptanal (22054-13-3) → Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester (75812-59-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / 4-(dimethylamino)pyridine / pyridine / 1.5 h / Ambient temperature

2: 1) potassium tert-butoxide / 1) 1 h, THF, room temp., 2) overnight at room temp.

With dmap; potassium tert-butylate; In pyridine;

DOI:10.1021/jo00315a049

Reference yield:

acetic acid 7-oxo-heptyl ester (29425-54-5) + 1,1-Diphenylphospholanium bromide (43017-36-3) → Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester (75812-59-8)

Guidance literature:

With potassium tert-butylate; Yield given. Multistep reaction; 1) 1 h, THF, room temp., 2) overnight at room temp.;

DOI:10.1021/jo00315a049

Reference yield:

Acetic acid (Z)-11-(diphenyl-phosphinoyl)-undec-7-enyl ester (75812-59-8) → (7Z,11Z)-7,11-hexadecadien-1-yl acetate (52207-99-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 1) aq. KOH, 2) p-toluenesulfonic acid / 1) MeOH, room temp., 2) CH₂Cl₂, room temp., 2 h

2: 1.) n-BuLi / 1.) hexane/THF, -78 deg C, 15 min; 2.) -78 deg C, 30 min

3: sodium hydride / dimethylformamide / 0.5 h / Ambient temperature

4: acetic acid / 0.5 h / Ambient temperature

With potassium hydroxide; n-butyllithium; sodium hydride; toluene-4-sulfonic acid; In acetic acid; N,N-dimethyl-formamide;

DOI:10.1021/jo00315a049

upstream raw materials:

acetic acid 7-oxo-heptyl ester

1,1-Diphenylphospholanium bromide

7-hydroxyheptanal

Downstream raw materials:

11-(2-tetrahydropyranyloxy)-4Z-undecenyldiphenylphosphine oxide

(7Z,11Z)-7,11-hexadecadien-1-yl acetate

1-acetoxyhexadeca-7Z,11E-diene