Ethyl 3-amino-2-cyclohexylpropanoate

Base Information

• Chemical Name: Ethyl 3-amino-2-cyclohexylpropanoate
• CAS No.: 91370-48-8
• Molecular Formula: C₁₁H₂₁NO₂
• Molecular Weight: 199.293
• Hs Code.: 2922499990
• Mol file: 91370-48-8.mol

Synonyms:cyclohexaneacetic acid, alpha-(aminomethyl)-, ethyl ester;

Chemical Property of Ethyl 3-amino-2-cyclohexylpropanoate

Chemical Property:

• Vapor Pressure: 0.00212mmHg at 25°C
• Refractive Index: 1.476
• Boiling Point: 290 °C at 760 mmHg
• PKA: 8.80±0.10(Predicted)
• Flash Point: 147 °C
• PSA: 52.32000
• Density: 1.002 g/cm³
• LogP: 2.40500
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

Ethyl3-amino-2-cyclohexylpropanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 3-amino-2-cyclohexylpropanoate

There total 3 articles about Ethyl 3-amino-2-cyclohexylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 1-cyclohexenylcyanoacetate (58567-40-1) → 3-amino-2-cyclohexyl-propionic acid ethyl ester (91370-48-8)

Guidance literature:

With hydrogen; nickel; In ethanol;

Reference yield:

→ 3-amino-2-cyclohexyl-propionic acid ethyl ester (91370-48-8)

Guidance literature:

With acetic acid; platinum; Hydrogenation;

DOI:10.1021/jo01102a004

Reference yield:

→ 3-amino-2-cyclohexyl-propionic acid ethyl ester (91370-48-8)

Guidance literature:

α-Cyclohexyliden-cyanessigsaeure-ethylester, H2 / Raney-Ni / absol.A. / 80-85grad / 40 at. / 2 h;

upstream raw materials:

ethyl 1-cyclohexenylcyanoacetate

Downstream raw materials:

2-cyclohexyl-beta-Alanine