C₂₁H₃₂O₅

Base Information

• Chemical Name: C₂₁H₃₂O₅
• CAS No.: 1338703-90-4
• Molecular Formula: C₂₁H₃₂O₅
• Molecular Weight: 364.482
• Mol file: 1338703-90-4.mol

Synonyms:C₂₁H₃₂O₅

Chemical Property of C₂₁H₃₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₃₂O₅

There total 17 articles about C₂₁H₃₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H32O5 → C21H32O5 (1338704-05-4) + C21H32O5 (1338703-90-4)

Guidance literature:

With anthracen-9-carboxylic acid; (R,R)-1,2-diphenylethylenediamine; In ethyl acetate; at 0 ℃; for 48h; optical yield given as %de; diastereoselective reaction;

DOI:10.1021/ol2024289

Reference yield:

C12H22OS2 → C21H32O5 (1338704-05-4) + C21H32O5 (1338703-90-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: tert.-butyl lithium / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; pentane / 0.08 h / -78 °C

1.2: 1 h / -78 °C

2.1: water; iodine; sodium hydrogencarbonate / acetonitrile / 0.08 h / 0 - 25 °C

3.1: sodium tetrahydroborate; diethyl methoxy borane / tetrahydrofuran; methanol / -78 - 0 °C

4.1: manganese(IV) oxide / dichloromethane / 3 h / 25 °C

5.1: 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-amino-1,2-diphenylethyl)thiourea; acetic acid / toluene / 72 h / 0 °C

With manganese(IV) oxide; sodium tetrahydroborate; 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-amino-1,2-diphenylethyl)thiourea; diethyl methoxy borane; water; iodine; tert.-butyl lithium; sodium hydrogencarbonate; acetic acid; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane; toluene; acetonitrile; pentane;

DOI:10.1021/ol2024289

Reference yield:

C24H38O4S2 → C21H32O5 (1338704-05-4) + C21H32O5 (1338703-90-4)

Guidance literature:

Multi-step reaction with 4 steps

1: water; iodine; sodium hydrogencarbonate / acetonitrile / 0.08 h / 0 - 25 °C

2: sodium tetrahydroborate; diethyl methoxy borane / tetrahydrofuran; methanol / -78 - 0 °C

3: manganese(IV) oxide / dichloromethane / 3 h / 25 °C

4: 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-amino-1,2-diphenylethyl)thiourea; acetic acid / toluene / 72 h / 0 °C

With manganese(IV) oxide; sodium tetrahydroborate; 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-amino-1,2-diphenylethyl)thiourea; diethyl methoxy borane; water; iodine; sodium hydrogencarbonate; acetic acid; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;

DOI:10.1021/ol2024289

upstream raw materials:

2-(1,3-dithian-2-yl)-2-methylpropanal

C₁₂H₁₆O₃

(S)-1-(benzyloxy)but-3-en-2-ol

(R)-2-(benzyloxy)-1-((S)-oxiran-2-yl)ethanol

Downstream raw materials:

C₅₀H₈₆O₁₂Si₃

C₅₀H₈₈O₁₂Si₃

C₄₃H₇₀O₁₀Si₂

C₅₅H₉₈O₁₀Si₄