Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine

Base Information

• Chemical Name: Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine
• CAS No.: 223418-05-1
• Molecular Formula: C₃₄H₄₅NOSi
• Molecular Weight: 511.823
• Mol file: 223418-05-1.mol

Synonyms:Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine

Chemical Property of Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine

There total 1 articles about Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

E-cinnamyltriphenylphosphonium chloride (69052-20-6) + 5-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-pentanal → Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine (223418-05-1)

Guidance literature:

With potassium tert-butylate; In diethyl ether; at -18 - 25 ℃;

DOI:10.1016/S0040-4039(99)00092-1

Reference yield: 88.0%

Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine (223418-05-1) → (5E,7E)-(S)-4-Dibenzylamino-8-phenyl-octa-5,7-dien-1-ol

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; Ambient temperature;

DOI:10.1016/S0040-4039(99)00092-1

Reference yield:

Dibenzyl-{(2E,4E)-(S)-1-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-5-phenyl-penta-2,4-dienyl}-amine (223418-05-1) → 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (5E,7E)-(S)-4-dibenzylamino-8-phenyl-octa-5,7-dienyl ester (223418-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / TBAF / tetrahydrofuran / Ambient temperature

2: 65 percent / NaH / tetrahydrofuran / Heating

With tetrabutyl ammonium fluoride; sodium hydride; In tetrahydrofuran;

DOI:10.1016/S0040-4039(99)00092-1

upstream raw materials:

E-cinnamyltriphenylphosphonium chloride

Downstream raw materials:

2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (5E,7E)-(S)-4-dibenzylamino-8-phenyl-octa-5,7-dienyl ester