(+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

Base Information

Chemical Name:(+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate
CAS No.:92622-42-9
Molecular Formula:C₂₄H₃₀O₁₂
Molecular Weight:510.495
Hs Code.:

Synonyms:(+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

Suppliers and Price of (+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

There total 5 articles about (+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 85382-87-2,118627-50-2,148152-74-3
methyl (4,5,7,8-tetra-O-acetyl-3-deoxy-α-D-manno-2-octulopyranosyl bromide)

: 100-51-6,185532-71-2
benzyl alcohol

: 92622-42-9,119437-82-0
Methyl-(benzyl-4,5,7,8-tetra-O-acetyl-3-desoxy-β-D-manno-2-octulopyranosid)onat

Guidance literature:: With Molekularsieb 4A; Ag⁽²⁺⁾*O₃Si^(2-); In dichloromethane; at -30 ℃; for 10h;
DOI:10.1016/0008-6215(90)80125-M

Reference yield: 95.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 92622-41-8
(+/-)-4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

: 92622-42-9
(+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

Guidance literature:: In diethyl ether; for 0.166667h;
DOI:10.1021/ja00291a030

Reference yield:

: 92622-38-3
(2R*,4R*,5S*,6R*)-4,5-bis(acetyloxy)-2-(benzyloxy)-2-(α-furyl)-6-vinyltetrahydropyran

: 92622-42-9
(+/-)-methyl 4,5,7,8-tetra-O-acetyl-2-O-benzyl-3-deoxy-D-manno-2-octulopyranosonate

Guidance literature:: Multi-step reaction with 4 steps

1: osmium tetraoxide / tetrahydrofuran; H₂O; CH₂Cl₂ / 4.5 h

2: pyridine / 4-(dimethylamino)pyridine / CH₂Cl₂ / 2 h

3: 86 percent / ruthenium dioxide (RuO₂), sodium periodate (NaIO₄) / H₂O; CCl₄; acetonitrile / 2 h

4: 95 percent / diethyl ether / 0.17 h

With pyridine; ruthenium(IV) oxide; sodium periodate; osmium(VIII) oxide; dmap; In tetrahydrofuran; tetrachloromethane; diethyl ether; dichloromethane; water; acetonitrile;
DOI:10.1021/ja00291a030