2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide

Base Information

Chemical Name:2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide
CAS No.:866431-47-2
Molecular Formula:C₂₆H₃₂N₄O₃
Molecular Weight:448.565
Hs Code.:

Synonyms:2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide

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Chemical Property of 2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide

Chemical Property:

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Technology Process of 2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide

There total 5 articles about 2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 866431-46-1
benzyl (2-{[(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)amino]carbonyl}phenyl)carbamate

: 866431-47-2
2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 3h;
DOI:10.1002/hlca.200590135

Reference yield:

: 866431-45-0
1-[(2-{[(benzyloxy)carbonyl]amino}benzoyl)amino]cyclopentane-1-carboxylic acid

: 866431-47-2
2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / tetrahydrofuran / 28 h / 20 °C

2: 98 percent / H₂ / Pd/C / methanol / 3 h / 20 °C

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1002/hlca.200590135

Reference yield:

: 866431-44-9
benzyl (2-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}phenyl)carbamate

: 866431-47-2
2-amino-N-(1-{[(1-{[(methyl)(phenyl)amino]carbonyl}cyclopentyl)amino]carbonyl}cyclopentyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / HCl / tetrahydrofuran; H₂O / 20 °C

2: 74 percent / tetrahydrofuran / 28 h / 20 °C

3: 98 percent / H₂ / Pd/C / methanol / 3 h / 20 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; water;
DOI:10.1002/hlca.200590135