10-Bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one

Base Information

Chemical Name:10-Bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one
CAS No.:34580-11-5
Molecular Formula:C₁₃H₇BrOS
Molecular Weight:291.168
Hs Code.:
DSSTox Substance ID:DTXSID301213116

Synonyms:SCHEMBL14474693;DTXSID301213116;CCG-49600;AKOS001021432;SR-01000639047-1;BRD-K66839551-001-01-8;Z56794893;10-Bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one;34580-11-5

Suppliers and Price of 10-Bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 10-Bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:289.94010
Heavy Atom Count:16
Complexity:339

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C3=C(C2=O)C=CS3)Br

Technology Process of 10-Bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one

There total 1 articles about 10-Bromo-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1622-55-5
9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one

: 4506-53-0
4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

: 34580-11-5
10-bromo-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

: 34580-10-4
9,10-dibromo-9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

: 126939-25-1
2-bromo-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

Guidance literature:: With N-Bromosuccinimide; benzyl peroxide; In tetrachloromethane; for 3h; Heating;

Reference yield:

: 34580-11-5
10-bromo-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

: 34580-13-7
ketotifen

Guidance literature:: Multi-step reaction with 2 steps

1: (i) THF, (ii) HBr, EtOH

2: (i) tBuOK, dioxane, (ii) aq. HCl

DOI:10.1002/hlca.19760590316

Reference yield:

: 34580-11-5
10-bromo-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-one

: 43076-17-1
4-(1-benzyl-piperidin-4-ylidene)-4,9-dihydro-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one

Guidance literature:: Multi-step reaction with 5 steps

1: (i) THF, (ii) HBr, EtOH

2: (i) tBuOK, dioxane, (ii) aq. HCl

3: toluene

4: aq. H₂SO₄ / butan-1-ol / 16 h / Heating

5: Na₂CO₃ / hexamethylphosphoric acid triamide / 18 h / Ambient temperature

With sulfuric acid; sodium carbonate; In N,N,N,N,N,N-hexamethylphosphoric triamide; toluene; butan-1-ol;
DOI:10.1002/hlca.19760590316