C₁₇H₂₂N₄O₅

Base Information

• Chemical Name: C₁₇H₂₂N₄O₅
• CAS No.: 1383736-61-5
• Molecular Formula: C₁₇H₂₂N₄O₅
• Molecular Weight: 362.385
• Mol file: 1383736-61-5.mol

Synonyms:C₁₇H₂₂N₄O₅

Chemical Property of C₁₇H₂₂N₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₂₂N₄O₅

There total 9 articles about C₁₇H₂₂N₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H26N4O6 → C17H22N4O5 (1383736-61-5)

Guidance literature:

C₂₄H₂₆N₄O₆; With boron trifluoride diethyl etherate; In dichloromethane; at 0 - 20 ℃;

With water; lithium hydroxide; In tetrahydrofuran;

DOI:10.1021/ol301461e

Reference yield:

4-((4R,5R)-4-acetyl-5-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)butanal (1383736-52-4) → C17H22N4O5 (1383736-61-5)

Guidance literature:

Multi-step reaction with 7 steps

1.1: silica gel; N-ethyl-N,N-diisopropylamine / toluene / 48 h / 75 °C

2.1: 2,2'-azobis(isobutyronitrile); bromine; potassium carbonate / dichloromethane / 40 °C / Inert atmosphere

2.2: 60 °C

3.1: sodium tetrahydroborate / methanol

4.1: hydrogenchloride; water / tetrahydrofuran / 48 h / 20 °C

5.1: dichloromethane

6.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane; water

7.1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C

With hydrogenchloride; sodium tetrahydroborate; 2,2'-azobis(isobutyronitrile); boron trifluoride diethyl etherate; water; bromine; silica gel; sodium hydrogencarbonate; potassium carbonate; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; dichloromethane; water; toluene; 1.1: Aldol condensation;

DOI:10.1021/ol301461e

Reference yield:

C16H16N4O2 → C17H22N4O5 (1383736-61-5)

Guidance literature:

Multi-step reaction with 5 steps

1: sodium tetrahydroborate / methanol

2: hydrogenchloride; water / tetrahydrofuran / 48 h / 20 °C

3: dichloromethane

4: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane; water

5: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C

With hydrogenchloride; sodium tetrahydroborate; boron trifluoride diethyl etherate; water; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1021/ol301461e

upstream raw materials:

4-((4R,5R)-4-acetyl-5-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)butanal

(4R,5R)-methyl 5-methyl-4-(pent-4-en-1-yl)-2-phenyl-4,5-dihydrooxazole-4-carboxylate

1-((4R,5R)-5-methyl-4-(pent-4-en-1-yl)-2-phenyl-4,5-dihydrooxazol-4-yl)ethanone

(4R,5S)-4,6-dimethyl-2-phenyl-3-oxa-1-azaspiro[4.4]nona-1,6-diene-7-carbaldehyde