methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate

Base Information

Chemical Name:methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate
CAS No.:848209-49-4
Molecular Formula:C₂₇H₂₇N₃O₆
Molecular Weight:489.528
Hs Code.:

Synonyms:methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate

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Technology Process of methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate

There total 1 articles about methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 848209-48-3
methyl (S)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}-3-(4-nitrophenyl)propionate

: 848209-49-4
methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; for 3h; under 2585.81 Torr;

Reference yield:

: 848209-49-4
methyl (S)-3-(4-aminophenyl)-2-{[(4R,5R)-5-(biphenyl-2-ylcarbamoyl)-[1,3]dioxolane-4-carbonyl]amino}propionate

: 5398-44-7
2,6-dichloropyridine-4-carboxylic acid

: 1253041-21-2
C₃₃H₂₈Cl₂N₄O₇

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
DOI:10.1016/j.bmcl.2010.07.069