2-(Ethyl{4-[2-(4-nitrophenyl)ethenyl]phenyl}amino)ethan-1-ol

Base Information

Chemical Name:2-(Ethyl{4-[2-(4-nitrophenyl)ethenyl]phenyl}amino)ethan-1-ol
CAS No.:122258-56-4
Molecular Formula:C₁₈H₂₀N₂O₃
Molecular Weight:312.368
Hs Code.:
DSSTox Substance ID:DTXSID10402773
Mol file:122258-56-4.mol

Synonyms:122258-56-4;2-[N-ethyl-4-[2-(4-nitrophenyl)ethenyl]anilino]ethanol;2-(Ethyl{4-[2-(4-nitrophenyl)ethenyl]phenyl}amino)ethan-1-ol;DTXSID10402773;OAFMCWZFMIQFBI-UHFFFAOYSA-N

Suppliers and Price of 2-(Ethyl{4-[2-(4-nitrophenyl)ethenyl]phenyl}amino)ethan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2-[Ethyl[4-[2-(4-nitrophenyl)ethenyl]phenyl]amino]ethanol 98%
250mg
$ 160.00

Total 3 raw suppliers

Chemical Property of 2-(Ethyl{4-[2-(4-nitrophenyl)ethenyl]phenyl}amino)ethan-1-ol

Chemical Property:

Melting Point:161-163 °C(lit.)
PSA：69.29000
LogP:4.10700
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:312.14739250
Heavy Atom Count:23
Complexity:378

Purity/Quality:

99% ^*data from raw suppliers

2-[Ethyl[4-[2-(4-nitrophenyl)ethenyl]phenyl]amino]ethanol 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CCO)C1=CC=C(C=C1)C=CC2=CC=C(C=C2)[N+](=O)[O-]
Uses Employed in the synthesis of a second-order chromophore covalently attached to a photofractive terpolymer.

Technology Process of 2-(Ethyl{4-[2-(4-nitrophenyl)ethenyl]phenyl}amino)ethan-1-ol

There total 8 articles about 2-(Ethyl{4-[2-(4-nitrophenyl)ethenyl]phenyl}amino)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: (E)-N-{2-[(tert-butyldimethylsilyl)oxy]ethyl}-N-ethyl-4-(4-nitrostyryl)aniline

: 122258-56-4
2-(ethyl(4-(2-(4-nitrophenyl)ethenyl)phenyl)amino)ethanol

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;
DOI:10.1039/c7ob03205f

Reference yield: 76.0%

: 104-03-0
4-nitrobenzeneacetic acid

: 63619-28-3
4-(N-ethyl-N-(2-hydroxyethyl)amino)benzaldehyde

: 122258-56-4
2-(ethyl(4-(2-(4-nitrophenyl)ethenyl)phenyl)amino)ethanol

Guidance literature:: With piperidine; at 100 - 120 ℃; for 3h;
DOI:10.1007/s10895-010-0611-7

Reference yield:

: N-{2-[(tert-butyldimethylsilyl)oxy]ethyl}-N-ethyl-4-ethynylaniline

: 122258-56-4
2-(ethyl(4-(2-(4-nitrophenyl)ethenyl)phenyl)amino)ethanol

Guidance literature:: Multi-step reaction with 3 steps

1: (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II) / toluene / 18 h / 20 °C

2: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / tert-Amyl alcohol; water / 21 h / 80 °C

3: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

With hydrogenchloride; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium carbonate; In 1,4-dioxane; tert-Amyl alcohol; water; toluene;
DOI:10.1039/c7ob03205f