ethyl p-(2-thenoyl)hydratropate

Base Information

• Chemical Name: ethyl p-(2-thenoyl)hydratropate
• CAS No.: 52779-95-0
• Molecular Formula: C₁₆H₁₆O₃S
• Molecular Weight: 288.367
• Mol file: 52779-95-0.mol

Synonyms:ethyl p-(2-thenoyl)hydratropate

Chemical Property of ethyl p-(2-thenoyl)hydratropate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl p-(2-thenoyl)hydratropate

There total 12 articles about ethyl p-(2-thenoyl)hydratropate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[4-(thien-2-ylcarbonyl)phenyl]propanoic acid (40828-46-4) → ethyl p-(2-thenoyl)hydratropate (52779-95-0)

Guidance literature:

With hydrogenchloride; In ethanol;

Reference yield:

4-(1-chloro-ethyl)-benzoyl chloride → ethyl p-(2-thenoyl)hydratropate (52779-95-0)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride / tin(IV) chloride / thiophene; dichloromethane

2: dimethyl sulfoxide

3: sulfuric acid; acetic acid / petroleumether; water

4: hydrogenchloride / ethanol

With hydrogenchloride; sulfuric acid; acetic acid; tin(IV) chloride; In thiophene; petroleumether; ethanol; dichloromethane; water; dimethyl sulfoxide;

Reference yield:

[4-(thiophene-2-carbonyl)-phenyl]-acetonitrile (52780-18-4) → ethyl p-(2-thenoyl)hydratropate (52779-95-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / water

2: sulfuric acid; acetic acid / petroleumether; water

3: hydrogenchloride / ethanol

With hydrogenchloride; sodium hydroxide; sulfuric acid; acetic acid; In petroleumether; ethanol; water;

upstream raw materials:

2-[4-(thien-2-ylcarbonyl)phenyl]propanoic acid

2-(4-fluorobenzoyl)thiophene

[4-(thiophene-2-carbonyl)-phenyl]-acetonitrile

4-(thien-2-ylcarbonyl)phenylacetic acid

Downstream raw materials:

N-hydroxy-2-[4-(thiophene-2-carbonyl)-phenyl]-propionamide