3H-Imidazo[4,5-g]quinazoline-4,8,9(5H)-trione, 6-(bromomethyl)-2,3-dimethyl- (9CI)

Base Information

Chemical Name:3H-Imidazo[4,5-g]quinazoline-4,8,9(5H)-trione, 6-(bromomethyl)-2,3-dimethyl- (9CI)
CAS No.:121732-15-8
Molecular Formula:C₁₂H₉BrN₄O₃
Molecular Weight:337.132
Hs Code.:
Mol file:121732-15-8.mol

Synonyms:3H-Imidazo[4,5-g]quinazoline-4,8,9(5H)-trione,6-(bromomethyl)-2,3-dimethyl- (9CI); NSC 622243

Suppliers and Price of 3H-Imidazo[4,5-g]quinazoline-4,8,9(5H)-trione, 6-(bromomethyl)-2,3-dimethyl- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3H-Imidazo[4,5-g]quinazoline-4,8,9(5H)-trione, 6-(bromomethyl)-2,3-dimethyl- (9CI)

Chemical Property:

PSA：97.71000
LogP:0.17130

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3H-Imidazo[4,5-g]quinazoline-4,8,9(5H)-trione, 6-(bromomethyl)-2,3-dimethyl- (9CI)

There total 5 articles about 3H-Imidazo[4,5-g]quinazoline-4,8,9(5H)-trione, 6-(bromomethyl)-2,3-dimethyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121732-19-2
ethyl 6-(α-methoxyacetamido)-1,2-dimethylbenzimidazole-5-carboxylate

: 121732-15-8
6-(bromomethyl)-2,3-dimethylimidazo<4,5-g>quinazoline-4,8,9(3H,7H)-trione

Guidance literature:: Multi-step reaction with 4 steps

1: 73 percent / 90percent HNO₃, H₂SO₄, acetic acid / 2.5 h / Ambient temperature

2: 86 percent / NH₃ (liquid) / methanol / 8 h / Ambient temperature

3: 71 percent / Na₂S₂O₄ / methanol; H₂O

4: 1.) 48percent aq. HBr, 2.) potassium nitrodisulfonate, KH₂PO₄ / 1.) 120 deg C, 6 h, 2.) H₂O, RT, 1.5 h

With potassium dihydrogenphosphate; sodium dithionite; potassium nitrososulfonate; sulfuric acid; ammonia; hydrogen bromide; nitric acid; acetic acid; In methanol; water;
DOI:10.1021/jo00276a022

Reference yield:

: 121732-21-6
2,3-dimethyl-6-(α-methoxymethyl)-4-nitroimidazo<4,5-g>quinazolin-8(3H,7H)-one

: 121732-15-8
6-(bromomethyl)-2,3-dimethylimidazo<4,5-g>quinazoline-4,8,9(3H,7H)-trione

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / Na₂S₂O₄ / methanol; H₂O

2: 1.) 48percent aq. HBr, 2.) potassium nitrodisulfonate, KH₂PO₄ / 1.) 120 deg C, 6 h, 2.) H₂O, RT, 1.5 h

With potassium dihydrogenphosphate; sodium dithionite; potassium nitrososulfonate; hydrogen bromide; In methanol; water;
DOI:10.1021/jo00276a022

Reference yield:

: 121732-20-5
ethyl 6-(α-methoxyacetamido)-1,2-dimethyl-7-nitrobenzimidazole-5-carboxylate

: 121732-15-8
6-(bromomethyl)-2,3-dimethylimidazo<4,5-g>quinazoline-4,8,9(3H,7H)-trione

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / NH₃ (liquid) / methanol / 8 h / Ambient temperature

2: 71 percent / Na₂S₂O₄ / methanol; H₂O

3: 1.) 48percent aq. HBr, 2.) potassium nitrodisulfonate, KH₂PO₄ / 1.) 120 deg C, 6 h, 2.) H₂O, RT, 1.5 h

With potassium dihydrogenphosphate; sodium dithionite; potassium nitrososulfonate; ammonia; hydrogen bromide; In methanol; water;
DOI:10.1021/jo00276a022