4-Quinolinecarboxylicacid,8-amino-(9CI)

Base Information

• Chemical Name: 4-Quinolinecarboxylicacid,8-amino-(9CI)
• CAS No.: 121689-23-4
• Molecular Formula: C₁₀H₈N₂O₂
• Molecular Weight: 188.186
• Mol file: 121689-23-4.mol

Synonyms:4-Quinolinecarboxylicacid,8-amino-(9CI)

Chemical Property of 4-Quinolinecarboxylicacid,8-amino-(9CI)

Chemical Property:

• PSA: 76.21000
• LogP: 2.09640
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98.5% ^*data from raw suppliers

8-Aminoquinoline-4-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Quinolinecarboxylicacid,8-amino-(9CI)

There total 4 articles about 4-Quinolinecarboxylicacid,8-amino-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-nitroquinoline-4-carboxaldehyde (69976-28-9) → 8-aminoquinoline-4-carboxylic acid (121689-23-4)

Guidance literature:

Multi-step reaction with 4 steps

1: KMnO₄; pyridine

2: concentrated H₂SO₄

3: platinum; ethanol / Hydrogenation

With pyridine; potassium permanganate; ethanol; sulfuric acid; platinum;

DOI:10.1021/ja01194a064

Reference yield:

8-nitro-quinoline-4-carboxylic acid (121689-22-3) → 8-aminoquinoline-4-carboxylic acid (121689-23-4)

Guidance literature:

Multi-step reaction with 3 steps

1: concentrated H₂SO₄

2: platinum; ethanol / Hydrogenation

With ethanol; sulfuric acid; platinum;

DOI:10.1021/ja01194a064

Reference yield:

8-nitro-quinoline-4-carboxylic acid ethyl ester (855613-71-7) → 8-aminoquinoline-4-carboxylic acid (121689-23-4)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; ethanol / Hydrogenation

With ethanol; platinum;

DOI:10.1021/ja01194a064

upstream raw materials:

8-nitroquinoline-4-carboxaldehyde

8-nitro-quinoline-4-carboxylic acid

8-nitro-quinoline-4-carboxylic acid ethyl ester