6'-EXOMETHYLENE SIMVASTATIN

Base Information

• Chemical Name: 6'-EXOMETHYLENE SIMVASTATIN
• CAS No.: 121624-18-8
• Molecular Formula: C₂₅H₃₆O₅
• Molecular Weight: 416.558
• Mol file: 121624-18-8.mol

Synonyms:Butanoicacid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-7-methyl-3-methylene-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenylester, [1S-[1a,7b,8b(2S*,4S*),8ab]]-

Chemical Property of 6'-EXOMETHYLENE SIMVASTATIN

Chemical Property:

• PSA: 72.83000
• LogP: 4.50570

Purity/Quality:

99% ^*data from raw suppliers

6’-ExomethyleneSimvastatin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Simvastatin A metabolite of Simvastatin.

Technology Process of 6'-EXOMETHYLENE SIMVASTATIN

There total 1 articles about 6'-EXOMETHYLENE SIMVASTATIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

simvastatin (123049-81-0,79902-63-9) → 6β'-hydroxy simvastatin (134523-09-4) + 6'-Exomethylene-Simvastatin (121624-18-8)

Guidance literature:

With D-glucose 6-phosphate; human CYP₃A₄; nicotinamide adenine dinucleotide phosphate; In dimethyl sulfoxide; pH=7.4; Concentration; Reagent/catalyst; Kinetics; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1124/dmd.110.036392

upstream raw materials:

simvastatin

Refernces