5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

Base Information

Chemical Name:5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide
CAS No.:1285514-03-5
Molecular Formula:C₂₃H₂₃N₃O₅S
Molecular Weight:453.519
Hs Code.:

Synonyms:5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

Suppliers and Price of 5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

There total 6 articles about 5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 462-08-8
pyridin-3-ylamine

: C₁₈H₁₈ClNO₅S

: 1285514-03-5
5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 25 ℃; for 1.08333h; Inert atmosphere;

Reference yield:

: 119-36-8,8024-54-2
methyl salicylate

: 1285514-03-5
5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

Guidance literature:: Multi-step reaction with 6 steps

1.1: chlorosulfonic acid / 1 h / 0 °C

2.1: dichloromethane / 2 h / 25 °C

3.1: potassium carbonate / acetone / 16 h / Reflux

4.1: water; lithium hydroxide / tetrahydrofuran / 6 h / 50 °C

4.2: pH 2

5.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0.52 h / 0 - 25 °C

6.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1.08 h / 0 - 25 °C / Inert atmosphere

With chlorosulfonic acid; oxalyl dichloride; water; potassium carbonate; N-ethyl-N,N-diisopropylamine; lithium hydroxide; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane; acetone;

Reference yield:

: 60638-81-5
5-chlorosulfonyl-2-hydroxy-benzoicacid methylester

: 1285514-03-5
5-(4-morpholinylsulfonyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide

Guidance literature:: Multi-step reaction with 5 steps

1.1: dichloromethane / 2 h / 25 °C

2.1: potassium carbonate / acetone / 16 h / Reflux

3.1: water; lithium hydroxide / tetrahydrofuran / 6 h / 50 °C

3.2: pH 2

4.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0.52 h / 0 - 25 °C

5.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1.08 h / 0 - 25 °C / Inert atmosphere

With oxalyl dichloride; water; potassium carbonate; N-ethyl-N,N-diisopropylamine; lithium hydroxide; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane; acetone;