4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

Base Information

Chemical Name:4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate
CAS No.:1448540-28-0
Molecular Formula:C₂₅H₂₀Cl₄N₂O₈
Molecular Weight:618.254
Hs Code.:

Synonyms:4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

Suppliers and Price of 4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

There total 9 articles about 4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₃H₂₀ClNO₈

: 545-06-2
trichloroacetonitrile

: 1448540-28-0
4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1021/jo4012442

Reference yield:

: 14131-63-6
D-glucosamine hydrochloride

: 1448540-28-0
4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

Guidance literature:: Multi-step reaction with 8 steps

1: sodium hydroxide / water

2: pyridine

3: boron trifluoride diethyl etherate / dichloromethane / 1 h / Reflux

4: sodium methylate / methanol / 3 h / 20 °C

5: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 1.5 h / 70 °C

6: pyridine / dichloromethane / 0.67 h / 0 °C

7: ammonium cerium (IV) nitrate / water; acetonitrile / 0.67 h / 0 °C

8: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 2 h / 0 °C

With pyridine; ammonium cerium (IV) nitrate; boron trifluoride diethyl etherate; sodium methylate; toluene-4-sulfonic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo4012442

Reference yield:

: 31505-45-0
2-deoxy-2-phthalimido-β-D-glucopyranose

: 1448540-28-0
4,6-di-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

Guidance literature:: Multi-step reaction with 7 steps

1: pyridine

2: boron trifluoride diethyl etherate / dichloromethane / 1 h / Reflux

3: sodium methylate / methanol / 3 h / 20 °C

4: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 1.5 h / 70 °C

5: pyridine / dichloromethane / 0.67 h / 0 °C

6: ammonium cerium (IV) nitrate / water; acetonitrile / 0.67 h / 0 °C

7: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 2 h / 0 °C

With pyridine; ammonium cerium (IV) nitrate; boron trifluoride diethyl etherate; sodium methylate; toluene-4-sulfonic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo4012442