1-(4-BUTYLPHENYL)ETHANOL

Base Information

• Chemical Name: 1-(4-BUTYLPHENYL)ETHANOL
• CAS No.: 125639-56-7
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.274
• Mol file: 125639-56-7.mol

Synonyms:1-(n-butylphenyl)ethyl alcohol

Chemical Property of 1-(4-BUTYLPHENYL)ETHANOL

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

1-(4-BUTYLPHENYL)ETHANOL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-BUTYLPHENYL)ETHANOL

There total 10 articles about 1-(4-BUTYLPHENYL)ETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-(4-butylphenyl)ethanone (37920-25-5) → (R)-1-(4-butylphenyl)ethanol (125638-82-6,125639-56-7,105364-43-0)

Guidance literature:

With Trimethyl borate; (S)-diphenylprolinol; dimethylsulfide borane complex; In tetrahydrofuran; toluene; at 25 - 30 ℃;

DOI:10.1021/jo035203v

Reference yield: 96.0%

1-(4-butylphenyl)ethanone (37920-25-5) → (S)-1-(4-butylphenyl)ethan-1-ol (105364-43-0,125639-56-7,125638-82-6)

Guidance literature:

1-(4-butylphenyl)ethanone; With (R)-(+)-3,3'-bis(4-fluorophenyl)-[1,1'-binaphthalene]-2,2'-diol; dibutylmagnesium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; lithium chloride; In n-heptane; toluene; at -40 ℃; for 3h; Inert atmosphere; Sealed tube;

With methanol; In n-heptane; toluene; at -40 - 20 ℃; for 0.5h; enantioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201908012

Reference yield: 79.0%

1-(n-butylphenyl)ethyl alcohol (125639-56-7) → (S)-1-(4-butylphenyl)ethan-1-ol (105364-43-0,125639-56-7,125638-82-6)

Guidance literature:

With nickel(II) chloride hexahydrate; cadmium sulphide; hydrogen; RuCl₂[(R)-DM-SEGPHOS]; potassium hydroxide; In water; tert-butyl alcohol; at 20 ℃; for 84h; under 7600.51 Torr; enantioselective reaction; Sealed tube; Irradiation;

DOI:10.1002/anie.202107570

upstream raw materials:

1-(4-butylphenyl)ethanone

aluminum isopropoxide

1-butylbenzene

4-(n-butyl)benzaldehyde

Downstream raw materials:

1-(4-butylphenyl)ethanone

ethyl 4-(4-butylphenyl)-2,4-dioxobutanoate

4-Butylaniline

(S)-1-(4-butylphenyl)ethan-1-ol