Benzylboronic acid pinacol ester

Base Information

• Chemical Name: Benzylboronic acid pinacol ester
• CAS No.: 121074-61-1
• Molecular Formula: C14H20 O2
• Molecular Weight: 220.312
• Hs Code.: 2931900090
• Mol file: 121074-61-1.mol

Synonyms:BENZYLBORONIC ACID PINACOL ESTER

Chemical Property of Benzylboronic acid pinacol ester

Chemical Property:

• Boiling Point: 269.6°Cat760mmHg
• Flash Point: 116.9°C
• PSA: 18.46000
• Density: 0.98g/cm³
• LogP: 3.12690

Purity/Quality:

99% ^*data from raw suppliers

Benzylboronic acid pinacol ester 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzylboronic acid pinacol ester

There total 1 articles about Benzylboronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 2,3-dimethyl-2,3-butane diol (76-09-5) → 2-(phenylmethyl)-4,4,5,5-tetramethyl-1,3-dioxolane (121074-61-1)

Guidance literature:

With iron(III) sulfate hydrate; palladium dichloride; In water; acetonitrile; at 45 ℃; for 48h; Reagent/catalyst; Solvent; Temperature; regioselective reaction;

DOI:10.1039/d1ob02227j

Reference yield: 85.0%

2-(phenylmethyl)-4,4,5,5-tetramethyl-1,3-dioxolane (121074-61-1) → phenylacetaldehyde (122-78-1)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 6h;

DOI:10.1039/d1ob02227j

Reference yield:

2-(phenylmethyl)-4,4,5,5-tetramethyl-1,3-dioxolane (121074-61-1) → benzyl radical (2154-56-5) + 4,4,5,5-Tetramethyl-1,3-dioxolan-2-ylium carbocation (33887-92-2)

Guidance literature:

In water; acetonitrile; at 20 ℃; Product distribution; Mechanism; Irradiation;

DOI:10.1021/ja00195a061

upstream raw materials:

styrene

2,3-dimethyl-2,3-butane diol

Downstream raw materials:

benzyl radical

4,4,5,5-Tetramethyl-1,3-dioxolan-2-ylium carbocation

phenylacetaldehyde

Refernces

• 1、 Matsumura, Satoko,Sato, Ruriko,Nakaoka, Sonoe,Yokotani, Wakana,Murakami, Yuka,Kataoka, Yasutaka,Ura, Yasuyuki. "Palladium-Catalyzed Aerobic Synthesis of Terminal Acetals from Vinylarenes Assisted by π-Acceptor Ligands". . p. 751 - 757. Retrieved 2017/03/13.