2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

Base Information

Chemical Name:2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate
CAS No.:1065081-80-2
Molecular Formula:C₂HF₃O₂*C₁₆H₁₅Cl₂N₅O
Molecular Weight:478.258
Hs Code.:

Synonyms:2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

Suppliers and Price of 2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

There total 4 articles about 2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1065079-14-2
tert-butyl [2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethyl]carbamate

: 76-05-1
trifluoroacetic acid

: 1065081-80-2
2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 0.5h;

Reference yield:

: 146821-47-8
dimethyl 2-(3,4-dichlorobenzyl)malonate

: 1065081-80-2
2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: diisobutylaluminium hydride / hexanes; dichloromethane / 3.5 h / -78 °C

1.2: 0.33 h

1.3: 20 °C

2.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine / N,N-dimethyl-formamide / 20 °C

3.1: dichloromethane / 0.5 h / 20 °C

With diisobutylaluminium hydride; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In hexanes; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1065081-55-1
6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

: 1065081-80-2
2-({[6-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-amino)ethanaminium trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine / N,N-dimethyl-formamide / 20 °C

2: dichloromethane / 0.5 h / 20 °C

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;