Methyl (1R,3S)-3-(chlorocarbonyl)-2,2-dimethylcyclopropane-1-carboxylate

Base Information

Chemical Name:Methyl (1R,3S)-3-(chlorocarbonyl)-2,2-dimethylcyclopropane-1-carboxylate
CAS No.:120591-67-5
Molecular Formula:C₈H₁₁ClO₃
Molecular Weight:190.627
Hs Code.:
DSSTox Substance ID:DTXSID10554367
Wikidata:Q82435327
Mol file:120591-67-5.mol

Synonyms:120591-67-5;methyl (1R,3S)-3-carbonochloridoyl-2,2-dimethylcyclopropane-1-carboxylate;Cyclopropanecarboxylic acid, 3-(chlorocarbonyl)-2,2-dimethyl-, methyl ester, cis- (9CI);DTXSID10554367;Methyl (1R,3S)-3-(chlorocarbonyl)-2,2-dimethylcyclopropane-1-carboxylate

Suppliers and Price of Methyl (1R,3S)-3-(chlorocarbonyl)-2,2-dimethylcyclopropane-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 1 raw suppliers

Chemical Property of Methyl (1R,3S)-3-(chlorocarbonyl)-2,2-dimethylcyclopropane-1-carboxylate

Chemical Property:

Boiling Point:75-77 °C(Press: 1 Torr)
PSA：43.37000
Density:1.226±0.06 g/cm3(Predicted)
LogP:1.19700
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:190.0396719
Heavy Atom Count:12
Complexity:235

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(C1C(=O)Cl)C(=O)OC)C
Isomeric SMILES:CC1([C@@H]([C@@H]1C(=O)Cl)C(=O)OC)C

Technology Process of Methyl (1R,3S)-3-(chlorocarbonyl)-2,2-dimethylcyclopropane-1-carboxylate

There total 2 articles about Methyl (1R,3S)-3-(chlorocarbonyl)-2,2-dimethylcyclopropane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 27335-35-9,27335-36-0,67911-25-5,76842-27-8,81831-72-3,81873-49-6,81873-51-0,81938-58-1,83542-42-1
(+/-)-(1R,2S)-2-(methoxycarbonyl)-3,3-dimethyl-1-cyclopropanecarboxylic acid

: 76842-28-9,120591-67-5
(1R,3S)-3-Chlorocarbonyl-2,2-dimethyl-cyclopropanecarboxylic acid methyl ester

Guidance literature:: With thionyl chloride; for 0.5h;

Reference yield:

: 76842-28-9,120591-67-5
(+/-)-3t-chlorocarbonyl-2,2-dimethyl-cyclopropane-r-carboxylic acid methyl ester

Guidance literature:: With thionyl chloride;
DOI:10.1002/jsfa.2740020908

Reference yield: 89.0%

: 76842-28-9,120591-67-5
(1R,3S)-3-Chlorocarbonyl-2,2-dimethyl-cyclopropanecarboxylic acid methyl ester

: 26770-99-0,27335-33-7,27335-34-8,41301-44-4,51424-62-5,55701-02-5,62138-41-4,67968-42-7,84710-48-5
methyl (+/-)-cis-3-formyl-2,2-dimethyl-1-cyclopropanecarboxylate

Guidance literature:: With hydrogen; sodium acetate; palladium on activated charcoal; In acetone; for 0.666667h; under 1241.2 Torr; Ambient temperature;