N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

Base Information

Chemical Name:N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine
CAS No.:908255-28-7
Molecular Formula:C₂₈H₃₀FN₇O₅
Molecular Weight:563.589
Hs Code.:

Synonyms:N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

Suppliers and Price of N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

There total 5 articles about N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 908255-27-6
N,N-(di-tert-butoxycarbonyl)-8-bromo-3-(para-fluorobenzyl)adenine

: 1452-77-3
pyridine-2-carboxylic acid amide

: 908255-28-7
N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In toluene; at 80 ℃; for 4h;
DOI:10.1016/j.bmc.2006.04.011

Reference yield:

: 908255-25-4
8-bromo-3-(4-fluorobenzyl)adenine

: 908255-28-7
N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / triethylamine; 4-(dimethylamino)pyridine / dimethylformamide / 2 h / 20 °C

2: 93 percent / dppf; Cs₂CO₃ / Pd₂dba3*CHCl₃ / toluene / 4 h / 80 °C

With dmap; 1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate; triethylamine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.bmc.2006.04.011

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 908255-28-7
N,N-(di-tert-butoxycarbonyl)-3-(para-fluorobenzyl)-8-picolinamidoadenine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / triethylamine; 4-(dimethylamino)pyridine / dimethylformamide / 2 h / 20 °C

2: 93 percent / dppf; Cs₂CO₃ / Pd₂dba3*CHCl₃ / toluene / 4 h / 80 °C

With dmap; 1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate; triethylamine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.bmc.2006.04.011