(αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

Base Information

Chemical Name:(αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide
CAS No.:938186-10-8
Molecular Formula:C₂₁H₂₃N₃O₃
Molecular Weight:365.432
Hs Code.:

Synonyms:(αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

Suppliers and Price of (αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of (αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

There total 3 articles about (αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 938186-07-3
(αS)-α-{[(benzyloxy)carbonyl]amino}-1-[(tert-butoxy)carbonyl]-N,N-dimethyl-1H-indole-4-propanamide

: 938186-10-8
(αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

Guidance literature:: With acetic acid; at 100 ℃; for 16h;
DOI:10.1002/hlca.200790058

Reference yield:

: 938186-04-0
(αS)-α-{[(benzyloxy)carbonyl]amino}-1-[(tert-butoxy)carbonyl]-1H-indole-4-propanoic acid

: 938186-10-8
(αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / Et₃N / acetonitrile / 3 h / -10 - 0 °C

2: 92 percent / AcOH / 16 h / 100 °C

With acetic acid; triethylamine; In acetonitrile;
DOI:10.1002/hlca.200790058

Reference yield:

: 460096-20-2
(S)-N^α-benzyloxycarbonyl-Nⁱⁿ-tert-butyloxycarbonyl-3-(indol-4'-yl)-alanine, methyl ester

: 938186-10-8
(αS)-α-{[(benzyloxy)carbonyl]amino}-N,N-dimethyl-1H-indole-4-propanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 1 h / 20 °C

2: 93 percent / Et₃N / acetonitrile / 3 h / -10 - 0 °C

3: 92 percent / AcOH / 16 h / 100 °C

With lithium hydroxide; acetic acid; triethylamine; In tetrahydrofuran; water; acetonitrile;
DOI:10.1002/hlca.200790058