1-Benzyl-1,4-dihydro-3-pyridinecarboxylic acid ethyl ester

Base Information

Chemical Name:1-Benzyl-1,4-dihydro-3-pyridinecarboxylic acid ethyl ester
CAS No.:116359-78-5
Molecular Formula:C₁₅H₁₇NO₂
Molecular Weight:243.305
Hs Code.:
DSSTox Substance ID:DTXSID601201601
Nikkaji Number:J725.082G

Synonyms:DTXSID601201601;1-Benzyl-1,4-dihydro-3-pyridinecarboxylic acid ethyl ester;Ethyl 1,4-dihydro-1-(phenylmethyl)-3-pyridinecarboxylate;116359-78-5

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Chemical Property of 1-Benzyl-1,4-dihydro-3-pyridinecarboxylic acid ethyl ester

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:243.125928785
Heavy Atom Count:18
Complexity:340

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=CN(C=CC1)CC2=CC=CC=C2

Technology Process of 1-Benzyl-1,4-dihydro-3-pyridinecarboxylic acid ethyl ester

There total 3 articles about 1-Benzyl-1,4-dihydro-3-pyridinecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1-Benzyl-3-ethoxycarbonyl-pyridinium; iodide

: 116359-78-5
1-Benzyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester

Guidance literature:: With sodium dithionite; sodium hydrogencarbonate; In water; ethyl acetate; at 40 ℃; for 1h;

Reference yield:

: 614-18-6
3-pyridinecarboxylic acid ethyl ester

: 116359-78-5
1-Benzyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / 3 h / 110 °C

2: 80 percent / sodium dithionite, NaHCO₃ / H₂O; ethyl acetate / 1 h / 40 °C

With sodium dithionite; sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 100-44-7
benzyl chloride

: 116359-78-5
1-Benzyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / 3 h / 110 °C

2: 80 percent / sodium dithionite, NaHCO₃ / H₂O; ethyl acetate / 1 h / 40 °C

With sodium dithionite; sodium hydrogencarbonate; In water; ethyl acetate;